Europe / Canada: is Marine patent irrelevant because they're going / went for RI indication only?
Any patent are irrelevant, since the first line of protection is the exclusivity (5 yrs NCER in the US): min 10 yrs in EU and (IRRC) 8 yrs in Canada. e.g in the EU - assuming approval by 12/31/2020 - V will be protected till 12/31/2030. Assuming no new indication, no extension of exclusivity the protection - after 12/31/2030 till 2033 - will be the R-IT patents.
China: If E in China is going for a Marine label, is there a Marine patent in China?
Should be … but could be invalidated based on the same ground.
If they are going for RI label, then is the Marine patent irrelevant?
At the first sight: yes. However I think R-IT ("should be") is weaker (mean chance is higher for invalidation) if MARINE patents are invalid.