Replies to post #232349 on Anavex Life Sciences Corp (AVXL)

[bb8675309]

Nidan. Great assessment. Thank you.

[polarbear77]

Agree completely, thank you Nidan for your valuable analysis, as per usual.

[Graniteguy]

Bravo nidan7500 for laying this all out. Those of us who are long this stock know the players here and understand what’s at stake. I’m very relieved to know that the decision makers are not all connected to the FDA in order to get this right, and that Anavex has independent trials running outside the United States.

[powerwalker]

nidan, you hit the nail on the head and your posts reminds us longs ...

https://www.encyclopedia.com/humanities/dictionaries-thesauruses-pictures-and-press-releases/speech-silver-silence-golden

Speech Is Silver, But Silence Is Golden
Views 2,015,435
Updated Dec 28 2019

speech is silver, but silence is golden proverbial saying, mid 19th century; meaning that discretion can be more valuable than the most eloquent words (see also the abbreviated form silence is golden).

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[Steady_T]

My assessment is and has been, they knew the FDA/NIH rules and processes were broken and worthless but they kept at it anyways. If that is not evidence of corruption then what is it? These people are smart.

I think you are misreading the situation. The FDA doesn't tell companies what trials to propose or what direction companies need to pursue in research. The FDA looks at proposed trials based on the documentation provided by the companies and decides if there is sufficient supporting evidence to support the trial and that the trial design is adequate to demonstrate the efficacy of the drug being tested.

More likely what you are seeing is the lack of medical/scientific understanding of AD cause or causes and a lack of diagnostic tests that are conclusive of the AD diagnosis.

The plaque hypothesis has been pursued mostly because it was one of the things that could be directly associated with AD. Tau tangles are in a similar situation. No one knows for sure what causes plaque buildup or Tau tangles although the science on both is progressing rapidly as has been shown by the article posted on this board.

It seems to me to be a safe bet that if the medical/scientific people at BP thought that they had a better idea to solve the AD dilemma they would choose it to spend the 100's of millions of Dollars they have spent in trials.

People's careers would be made by finding a successful drug for AD.

We may well see that with 2-73.