Replies to post #254864 on NorthWest Biotherapeutics Inc (NWBO)

[pgsd]

I fully realise that Direct could be validated sooner, the phase 1 results showed very promising SD data at 6 weeks however, it is not something I am relying on.

[jondoeuk]

Not a single patient responded to Direct and maybe this is why the PhII never happened*

* From NWBO's site: ''The Phase II stage of the trial will focus on efficacy. The primary measure of efficacy will be regression (i.e., shrinkage or elimination) of the patient’s existing inoperable tumors. Such regression is a rapid endpoint: if it is going to occur, is anticipated to occur within a couple months of treatment.'' https://nwbio.com/dcvax-direct-phase-iii-for-all-types-of-inoperable-solid-tumor-cancers/