Nidan,
My take on the extensions, fwiw:
Precision Medicine is all about data mining to get the strongest correlations from and for response(responders)/non-response (non-responders) to a specific treatment for a specific ailment.
Much, much more data to be mined from an experiment where a specific patient is treated for a specific ailment with a placebo and then SWITCHED over to an active drug. (2 controls - same patient and same disease state, 1 variable - without drug, with drug. Great science - this will enhance, enrich, boggle the mind with stat sig data correlations - extremely AI friendly environment).
Now, you do the rest...
We Got This!
Bio