Replies to post #155913 on Kraig Biocraft Laboratories Inc (KBLB)

[bananarama]

"Imagine a new platform worm that is so much more efficient at producing non-native proteins like insulin? What would that be worth?"

GREAT POST, GTman! I appreciate your knowledge about silkworms. These last two lines above from your post sum it up perfectly! KBLB IS PRICELESS!

[yankeeclipper]

GTman1- AWESOME POST.

With your background in the biological sciences, we're going to have to reconsider what KBLB's IP is really worth to the medical industry and the huge Fortune 1000 companies in it.

LCP chimeric silkworms bred up as the vessel for medical uses and something more than high strength ss fiber - it's mind blowing what that is worth. That IP alone could be spun out to the medical industry. Kim and Trevor's collaboration on this IP path is brilliant -IMO.

Suddenly KBLB's IP alone could be worth 10X more than .50 per share.

Hopefully some other board posters with biological science backgrounds will weigh in on this.

Best regards - yankee

[Cluck Kent]

I concur, that's actually been my observation for some time now, that one of the really great accomplishments here is the processes and the point where Kraig was able to 'stabilize' this genetic process they have and to 'control' and 'design' with it, as when they announced previously being able to control the strength and quality of the Spider Silk itself for different purposes. My understanding from many years of studying genetics and breeding in plants, insects and animals, is that there was always a 'hump' difficulty not just in 'traditional' hybridization, but in genetic implantation as well, since there was always the 'problem' that the process wasn't 'true' as far as the 'new' characteristics and the implants would become 'recessive' and wouldn't hold within a few short generations of breeding. What's really happening here is we're genetically creating 'new species' without those 'new' characteristics being necessary for it's survival or adaptation in the ecological environment connected to the planet for thousands of years, so normally a new species or 'mutation' without that 'connection' would either go extinct or new traits would eventually become 'hidden' recessive and disappear like the human appendix and much of our body hair we no longer need. Even the 'stabilized' silk gene's Kraig's created could become dormant or go extinct if these worms got into the natural environment, since even the Bombyx Mori silkworm species we're using no longer is found in it's wild form anymore and has disappeared after thousands of years of domestic breeding. The Bombyx only exists within the human silk industry, and has lost it's ability to fly, since breeders obviously bred big fat one's that couldn't get away and cause them to lose money. There are some variants in the wild but not this exact species. Long, long story short, Kraig's processes and patents for this gene work are indeed important for any gene work since they produce stable traits that can breed 'true' from generation to generation and not just with silkworms either. They've improved on Dna implantation 'itself' that's tremendously valuable for pretty much any organism that's used. This work and their patents are unbelievably valuable, especially to the medical industry as you've pointed out!

An interesting and related info regarding 'domesticated' animals that overturned the theory of how dogs evolved comes from old footage of a researcher in Russia in the early 1950s who was hired to create 'tame' 'silver foxes' for that fur industry. It was considered a 'failure' because within approximately 25 years of inbreeding the most tames ones to each other, their coats became multi colored like dogs and domestic horses and cattle (pied colored like holsteins), their ear went floppy like dogs, and even started barking and behaving like dogs! It wasn't until recently that this attempt was rediscovered and it's been realized that all these same traits in domesticated mammals are related to the production of 'adrenaline' which sparks aggression in mammals, and that when adrenaline is reduced or bred out for more passive traits it's linked to the physical traits in modern dogs, so the theories that dogs evolved over millions of years from wolves was trashed, even though the wolf may have been a progenitor of many other species of canines like coyotes and silver foxes for instance. I once once told by a dog owner that his 'white' (uncommon for camouflage except in constant snow environments in nature) lab had a nervous complex to loud noise that would shorten the dog's life because being all white he completely lacked 'adrenaline!'. In other words, adrenaline serves a purpose, and if humans had none we probably couldn't react to survive in danger situations, but 'modulating' or having less of it keeps us from killing one another and being 'wild'. One also notes that 'one trait' in any species is probably linked to many others that can obviously change an organism, plant, or animals, entire physical and/or emotional makeup! The intricacies of evolution, no matter how good the science are shown to be so extensive through millions of years of evolution, I don't know if we will ever entirely understand it with all the gene research in the world. Like the famous quote from Jurassic park that you can't one up nature, or 'life will find a way!'

Here, info about the silver fox research and its genetic connections for humans as well, https://www.nationalgeographic.com/animals/2018/08/fox-dogs-wild-tame-genetics-study-news/

[rayovac812]

Go GT.

You and arachnodude get top posts for the week. When this is spelled out for people according to share price, it is going to be too late. Manufacturers of current proteins are making calls as they read todays news, over the coming weeks. Good times.....

[golferman]

Wow.... this area of non-native proteins could be Hugh.

Hope to hear more on this breakthrough.

[TRUISM]

I don't think people realize how significant this news really is. If Kraig Labs has been able to develop ways to produce non-native proteins other than silks, this could be game changing. I know they were working on the Knock Out worms for a while. It looks like they may have succeeded in perfecting the process.

It will be interesting to see the patent applications once available for viewing online.

As you know, more markets equates to additional space required to satisfy efforts....

The need for the proposed 50 million dollar project infusion is becoming that much clearer....



Blessings
TRUTH