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Re: GTman1 post# 155913

Wednesday, 05/22/2019 8:32:49 PM

Wednesday, May 22, 2019 8:32:49 PM

Post# of 278356
I concur, that's actually been my observation for some time now, that one of the really great accomplishments here is the processes and the point where Kraig was able to 'stabilize' this genetic process they have and to 'control' and 'design' with it, as when they announced previously being able to control the strength and quality of the Spider Silk itself for different purposes. My understanding from many years of studying genetics and breeding in plants, insects and animals, is that there was always a 'hump' difficulty not just in 'traditional' hybridization, but in genetic implantation as well, since there was always the 'problem' that the process wasn't 'true' as far as the 'new' characteristics and the implants would become 'recessive' and wouldn't hold within a few short generations of breeding. What's really happening here is we're genetically creating 'new species' without those 'new' characteristics being necessary for it's survival or adaptation in the ecological environment connected to the planet for thousands of years, so normally a new species or 'mutation' without that 'connection' would either go extinct or new traits would eventually become 'hidden' recessive and disappear like the human appendix and much of our body hair we no longer need. Even the 'stabilized' silk gene's Kraig's created could become dormant or go extinct if these worms got into the natural environment, since even the Bombyx Mori silkworm species we're using no longer is found in it's wild form anymore and has disappeared after thousands of years of domestic breeding. The Bombyx only exists within the human silk industry, and has lost it's ability to fly, since breeders obviously bred big fat one's that couldn't get away and cause them to lose money. There are some variants in the wild but not this exact species. Long, long story short, Kraig's processes and patents for this gene work are indeed important for any gene work since they produce stable traits that can breed 'true' from generation to generation and not just with silkworms either. They've improved on Dna implantation 'itself' that's tremendously valuable for pretty much any organism that's used. This work and their patents are unbelievably valuable, especially to the medical industry as you've pointed out!

An interesting and related info regarding 'domesticated' animals that overturned the theory of how dogs evolved comes from old footage of a researcher in Russia in the early 1950s who was hired to create 'tame' 'silver foxes' for that fur industry. It was considered a 'failure' because within approximately 25 years of inbreeding the most tames ones to each other, their coats became multi colored like dogs and domestic horses and cattle (pied colored like holsteins), their ear went floppy like dogs, and even started barking and behaving like dogs! It wasn't until recently that this attempt was rediscovered and it's been realized that all these same traits in domesticated mammals are related to the production of 'adrenaline' which sparks aggression in mammals, and that when adrenaline is reduced or bred out for more passive traits it's linked to the physical traits in modern dogs, so the theories that dogs evolved over millions of years from wolves was trashed, even though the wolf may have been a progenitor of many other species of canines like coyotes and silver foxes for instance. I once once told by a dog owner that his 'white' (uncommon for camouflage except in constant snow environments in nature) lab had a nervous complex to loud noise that would shorten the dog's life because being all white he completely lacked 'adrenaline!'. In other words, adrenaline serves a purpose, and if humans had none we probably couldn't react to survive in danger situations, but 'modulating' or having less of it keeps us from killing one another and being 'wild'. One also notes that 'one trait' in any species is probably linked to many others that can obviously change an organism, plant, or animals, entire physical and/or emotional makeup! The intricacies of evolution, no matter how good the science are shown to be so extensive through millions of years of evolution, I don't know if we will ever entirely understand it with all the gene research in the world. Like the famous quote from Jurassic park that you can't one up nature, or 'life will find a way!'

Here, info about the silver fox research and its genetic connections for humans as well, https://www.nationalgeographic.com/animals/2018/08/fox-dogs-wild-tame-genetics-study-news/
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