Replies to post #208485 on NorthWest Biotherapeutics Inc (NWBO)

[CogDiss 1188X]

Flipp, excellent point. Even approaches which we hope to make obsolete (like chemo/radiation) may play a legitimate, though limited, role in the future.

[flipper44]

To me, Dr. Ashkan’s intratumoral glass pipette assisted laser surgical efforts are consistent with the likelihood DCVax-l works better and more safely in once thought to be previously inoperable patients if surgery can in fact be implemented. A patient thereafter followed by treatment with DCVax-l or DCVax-Direct would (ahead of time) have the tumor microenvironment control temporarily dislodged, antigen uptake potential increased and sufficient space for any immune response induced swelling (aka: IRIS) from subsequent t-cell and NK cell tumor infiltration. Setting the stage for more favorable conditions to promote efficacious DCVax therapeutic intervention, IMO.