Replies to post #206476 on NorthWest Biotherapeutics Inc (NWBO)

[exwannabe]

Cog, the Coley concept was tried over and over with at most one possible minor win (BCG in bladder cancer). It was not until the last 20 years that we understand the immune system and can create biologics that progress has been made.

There has been a hell of a lot of work put into immuno agents in the last 20 years. It is not like it has been ignored. More than a few billion dollars in DCs alone.

I do not know the numbers, but I doubt much has been put into standard chemoe in the last 10-15 years. Some minor tweeks is all.

A lot has gone into targeted molecular inhibitors and MABs. Is this a waste? I am sure the patients living longer w/o chemo on these agents would not think so.

Everybody loves the idea of training the immune system to do the job. But while we try to figure out this very difficult challenge, there are patients to be treated.

[sentiment_stocks]

“Drugs can only repress symptoms: they cannot eradicate disease. The true remedy for all diseases is Nature’s remedy .... There is at bottom only one genuinely scientific treatment for all diseases, and that is to stimulate the phagocytes. Stimulate the phagocytes. Drugs are a delusion”.

Wow, I did not know that. How extremely prescient of Mr. Shaw. Especially when this was still during a time when bloodletting persisted, even if it was fading as a practice.

Bloodletting persisted into the 20th century and was recommended in the 1923 edition of the textbook The Principles and Practice of Medicine. The textbook was originally written by Sir William Osler and continued to be published in new editions under new authors following Osler's death in 1919.
https://en.wikipedia.org/wiki/Bloodletting

He also wrote,

Progress is impossible without change, and those who cannot change their minds cannot change anything.

It looks like he had plenty of worthy things to say.
https://www.brainyquote.com/authors/george_bernard_shaw