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Re: CogDiss 1188X post# 206476

Thursday, 01/03/2019 4:13:56 PM

Thursday, January 03, 2019 4:13:56 PM

Post# of 700579
Cog, the Coley concept was tried over and over with at most one possible minor win (BCG in bladder cancer). It was not until the last 20 years that we understand the immune system and can create biologics that progress has been made.

There has been a hell of a lot of work put into immuno agents in the last 20 years. It is not like it has been ignored. More than a few billion dollars in DCs alone.

I do not know the numbers, but I doubt much has been put into standard chemoe in the last 10-15 years. Some minor tweeks is all.

A lot has gone into targeted molecular inhibitors and MABs. Is this a waste? I am sure the patients living longer w/o chemo on these agents would not think so.

Everybody loves the idea of training the immune system to do the job. But while we try to figure out this very difficult challenge, there are patients to be treated.

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