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Whalatane

11/29/18 6:41 PM

#164098 RE: lowlevelowl88 #164094

lowlevel ..re EVAPORATE ...why it won't halt at interim ...will be surprised if it does

1) Fairly low risk inclusion requirements

Patients with at least 1 angiographic stenosis with at least 20% narrowing by coronary computed tomography angiography (CTA).

compared to CHERRY ...which from memory inclusion required previous PCI ( stents )
and R-IT where most had prior MI or previous CV event

METHODS: CHERRY
We enrolled 193 CHD patients who underwent percutaneous coronary intervention (PCI) in six hospitals.


2). They'll want as much data as possible ...event lines take time to separate .
If they didn't stop R-IT at Interim 2 ( which it seems like they could have ) ..then doubt if they'll stop EV .
JMO
Kiwi

sts66

11/30/18 1:33 PM

#164245 RE: lowlevelowl88 #164094

Patients in CHERRY were Japanese, already had good EPA/AA levels - could take longer for 'mericans with crappy high O6/AA diets to respond to 4 g of EPA per day - and I don't mean EPA/AA levels changing (happens fast), I mean plaque regression. Size and severity of plaque between the two groups of patients could also be very different.