Replies to post #162169 on Amarin Corp Plc (AMRN)

[rosemountbomber]

I saw a tweet from Bhatt posted on Stocktwits where he stated a Nobel Prize is waiting for anyone who presents MOA for EPA.

[ilovetech]

This is not the first time that JL posted this wonderful explanation of how the inflammatory system evolved. I really believe it should be pinned for future reference.

Thanks
ILT

[SonamKapoor]

EPA ancient molecule - yes, built for fast(er) action like a soccer midfielder. :-D



Earth's core as O Mg Si Fe. We know Carl Sagan who said we are all descended from stardust.



Lynn Margulis, his late first wife, said "the animal's food, becomes the animal's body" or “Life is a planetary level phenomenon and the Earth has been alive for at least 3000 million years. To me the human move to take responsibility for the living Earth is laughable - the rhethoric of the powerless. The planet takes care of us, not we of it. Our self inflated moral imperative to guide a wayward Earth or heal a sick planet is evidence of our immense capacity for self-delusion. Rather, we need to protect us from ourselves.”

Lynn Margulis interview on symbiogenesis

Lynn picked up the story where Carl left off.

Also, Neil Shubin, paleontologist and evolutionary biologist: Your Inner Fish

Cell manifest destiny: https://prezi.com/efljo-431pty/cell-analogies/

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We don't want cavitation in car shocks:


Or on the back end of our submarines - Nat Geo Navy cavitation

But, we want cavitation in the kitchen - how a blender works

Or in the lab when we need to pull apart cell bits to study things like specialized pro-resolving mediators (SPMs) made from EPA, etc -



Or for new ways to deliver the drugs -



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Which leads back to cavitation as a possible theory on how earthlings began:



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Longer chain compounds last longer and are in deep storage to possibly (among other reasons), tide body/cells over during drought periods such as with Vit K2 or DHA for their shorter chained siblings.





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The germ/microbe/virus reason for inflammation fits like the continental drift theory. We've been in a constant state of battle with all the infectious disease spreading vectors like hookworm, mosquitoes, ticks, mice, bats, etc. Mosquitoes and ticks have perfected their anti-coagulants to keep their blood smorgasbord going. So, we get sickle-cell anemia adaptations in Africa. And Vit K differences like in Asians and AA genetic adaptations, too, all depending on what localized battles might be going on such as against Japanese encephalitis or malaria variants.

And what about horseshoe crabs? They have blue copper based blood that coagulates really quickly and use amebocytes to fight infections. Deep sea vent origins 450 million years ago = fun quirks today.