Replies to post #193290 on NorthWest Biotherapeutics Inc (NWBO)

[Doc logic]

JerryCampbell,

Yes, I agree that all of us can have "a really bad day at the office" especially when we get passionate about something and see what we sense as a major injustice being perpetrated against a "Nobel"/noble type cause. Fortunately, in spite of all the hope for a quick turn around in share price that the accolades you mentioned appeared to portend, evidence now points to an improved product and outcomes for patients who were more recently enrolled in this Phase 3 trial. HE depended on the Phase 3 finishing up sooner rather than later but apparently improved manufacturing and waiting on OS and then the long tail was chosen instead due to a belief that PFS primary alone would not be enough to assure approval. This made the tradeoff between HE revenue and weaker results a very poor one. This became especially clear in light of the need to wait for longer term results over the course of IO trials highlighted by the failures of others to do so.

Championing a therapy or company that shows early potential to demonstrate success in treating a deadly disease is not pumping. Those who understand the totality of market forces and expected time frames may call it that because early excitement might give rise to a temporarily unsustainable price increase due to necessarily longer term time frames involved in validation and commercialization. On the other hand, every company to be successful must have a great sales force and often times that starts with the CEO. If the product or tech generates little resistance from others due to lack of Direct competition or displacement potential of other technologies held by powerful interests then that technology will be embraced and championed by those same interests eager to join in the growth potential. If the tech is disruptive then quite the polar opposite response should be expected. In that case almost anything anyone might say positive about even a very promising technology will be shot down, discredited and called pumping. Mr. Pearlstein came to the defense of a company he thought had demonstrated some early potential and is being called a supporter of pumpers by you. So tell me, is NWBO supporting a potentially disruptive technology and being hammered along with anyone who supports this claim because of this or is NWBO a run of the mill biotech scam. Seems like a pretty simple choice to make and take sides on. Care to give a clear answer on your position? Best wishes.