Replies to post #148018 on Amarin Corp Plc (AMRN)

[smarterer]

Just wondering how you and others came across AMMRN and why you stuck with it .
I remember you were actively discussing AMRN on the Yahoo board ....then after Adcom did you just set it aside as " sunk cost " and forget about it until recently.

Hi Kiwi,

I've blamed you on this board for my foray into AMRN. Been a long time--think it was Feb of 2011, but maybe it was 2010--had been playing around in Oncolytics, a Canadian biopharm that was looking at ways to use a proprietary reovirus to treat a number of things. For a while it looked promising addressing e. coli infections... But that failed, and I was looking for ideas. Think I saw a convo between you and DewDiligence on his iHub board, and some mention of JL as a pretty bright guy.

Looked into AMRN on the Yahoo board, read a lot of informative postings, discovered that you guys weren't wrong in calling JL both bright and at times a bit abrasive. Having grown up in NY and NJ, and gone to grad school in Boston, 'abrasive' just sounded 'straightforward' for the most part.

After Adcom, I sold out (25k shares at the time) completely as it was dropping. Got out between $6 and $3, trying to preserve capital. Knew it was in trouble for a while, but also knew it had tons of promise, so kept it on my radar. Meanwhile had some interesting life challenges that took precedence, but in 2015 life stabilized, and I accumulated several thousand shares over the ensuing three years. So for me it wasn't a sunk cost, but a belief that this was likely--I put odds at 80%+ in my internal analysis--to be at least modestly successful. (One of the lessons the economists at Harvard drummed into me during grad school is that you know more than you think, so attempt to quantify everything. Those that do are more accurate forecasters than those who do not, even though you may be wildly off at times.)

One of the reasons I like these chat rooms is I learn from everyone. Psychology/mood can be really informing, and I get lots of ideas to look into for new investments. Also get challenged on my thinking, also a good thing. You are particularly adept ;-)

Anyway, that's my story. Curious to hear others'.

[funnygi2]

Hi G,

Funny you should ask. Pure dumb luck, although as Branch Rickey said "luck is the residue of design". A friend "back east" walked into a bank one day and the branch manager started telling him all about the stock - "everybody on Wall St. is talking about this stock blah blah blah" - (this was back in 2012). I was "stupid" enough to take a gamble on it....a few months before that slide that began in late '12.
Although the last six years have been damn nerve-wracking, I did buy more at lower prices....though not at 80 cents a share LOL. At that point it didn't make any sense to sell. Plus I kept thinking of what JL said - "I feel like I'm betting on the outcome of a race that's already been run" (Jelis)

Hope to see you in SF or LV.

[rosemountbomber]

Kiwi,

I used to have customers coming in looking for some alternative to prescriptions they were given for Lovaza (actually Omacor before the name change).

Then at some point I found out about Vascepa and knew that pure EPA was superior to a mixture product. I invested early in 2012 for the runup to Marine. Intentions were to sell on the news of approval, but price began to drop. Listened to CC given by Joe Z and believed his hype about buyout. Continued to hold as it dropped hoping that the Adcom would be successful and give a boost to stock price. No such scenario. Continued to buy and average down. Didn't get any at 80 cents, but noticed the other day when looking at some lots, that I got some at 99 cents. Turned my kid onto it and I believe is cost is around 1.01. Took small amount of profit after R-I announcement jump and since those were the oldest shares not much of a capital gain on those lots.

Will have to really think carefully about any further sales as those lots carry large gains potentially. Might need to split over different years.

[VuBru]

Kiwi - I came across AMRN by accident. I had no intention of investing in individual stocks, but had some money sitting around earning nothing. I accidentally clicked on a link, which took me to a Motley Fool article on a potentially undervalued stock with risk but very high potential upside. It was about $2.50/sh at that point, but by the time I learned more about it (found iHub board, articles) it had increased to $3. I ended up with 27,000 shares at $3, although it was not always easy convincing my wife to take a chance on this. She now thinks I am a financial genius ;-)

[Dancing in the dark]

in april 2007, i became a stuckholder in Amarin while attempting to trade a hopeful rebound after:

AMARIN REPORTS TOP-LINE RESULTS OF TWO PHASE III STUDIES OF MIRAXION IN HUNTINGTON’S DISEASE

Amarin Corporation plc (NASDAQ: AMRN) (“Amarin” or the "Company") today announces top-line results from its two Phase III clinical trials of Miraxion to treat Huntington’s disease (HD). The Company conducted two Phase III double-blind, placebo-controlled studies in which HD patients were randomized to receive either placebo or 2 grams (1 gram twice daily) of Miraxion daily for six months. Study data showed no statistically significant difference in either study between Miraxion and placebo with regard to the primary and secondary endpoints.

These top-line findings are inconsistent with earlier clinical trial data that showed statistical significance in a subset of HD patients with a CAG repeat length of less than or equal to 44.

The primary endpoint of the trials was a change in the Total Motor Score 4 (TMS-4) component of the Unified Huntington’s Disease Rating Scale (UHDRS). TMS-4 has been shown to be a sensitive measure of movement disorder in patients with HD. In addition, secondary endpoints included cognition and Total Functional Capacity outcomes. Miraxion was found to be safe and well-tolerated by patients.

Commenting on today’s announcement, Rick Stewart, Chief Executive Officer of Amarin, said, “We are extremely surprised and disappointed by these top-line results, and we are analyzing the data in order to better understand the full and complete data set and outcomes. We are particularly disappointed that, at this time, we are not in a position to bring any positive news to those patients who are suffering from this devastating disease and to the broader HD community.”

“Despite this setback with Miraxion to treat HD, we remain committed to developing Amarin’s substantial central nervous system (CNS) development pipeline.” commented Mr. Stewart. “We continue to evaluate the potential of Miraxion in treating CNS disorders and specifically our next steps with respect to the HD trials. We also intend to progress the development of our novel, oral formulation of apomorphine to treat the ‘off’ episodes in advanced Parkinson’s disease patients, our recently in-licensed nasal formulation of lorazepam for the out-patient treatment of emergency seizures in epilepsy patients and our proprietary combinatorial lipid pre-clinical program in CNS disorders and other indications.” concluded Mr Stewart.

Thomas Lynch, Amarin’s Chairman, added “Our commitment to neurology research and product development remains steadfast and we will continue to pursue other in-licensing opportunities while we advance our broad pipeline of products to treat CNS disorders.


then things grew worse:

06/08/2007
AMARIN RECEIVES NASDAQ NOTIFICATION RELATED TO MINIMUM BID PRICE
Amarin will be provided with 180 calendar days, or until December 3, 2007, to regain compliance.

yet hopeful:

10/10/2007
AMARIN ANNOUNCES INITIATION OF CARDIOVASCULAR DEVELOPMENT STRATEGY
Capitalizing on Known Therapeutic Benefits of Unsaturated Fatty Acids in Cardiovascular Disease
Amarin intends to commence a series of clinical trials with AMR 101 (97% pure EPA) in dyslipidemia, the first of which will commence by the end of this year. In addition, Amarin intends to commence investigation of new compounds from its existing development portfolio for the treatment of metabolic syndrome and dyslipidemia.

11/29/2007
AMARIN COMMENCES FIRST CLINICAL TRIAL IN CARDIOVASCULAR PROGRAM
Initiates Phase I Clinical Trial to Evaluate Ultra-Pure Ethyl EPA-Niacin for Treatment of Niacin- Induced Flushing
Announced that it has commenced a phase I clinical safety and efficacy trial in volunteers. The trial will evaluate the co-administration of ultra-pure ethyl EPA and niacin on niacin induced flushing. Flushing is a common side effect of niacin treatment which significantly limits patient compliance.

but then i became really stuck:

01/18/2008
AMARIN PROVIDES BUSINESS UPDATE AND ANNOUNCES IMPLEMENTATION OF REVERSE STOCK SPLIT
Shareholders approved a 1 for 10 reverse split of each of its Ordinary Shares. Following the reverse split, there are now 14,003,237 Ordinary Shares in issue.
Share price was $0.23 when it reverse split 10 to 1 to $2.30.

it was at this point i decided there was the potential for enough upside to recoup my original capital and then some, if amarin could be successful with their CARDIOVASCULAR DEVELOPMENT STRATEGY

07/22/2008
AMARIN PROCEEDING TO PHASE 3 WITH AMR101 FOR HYPERTRIGLYCERIDEMIA
AMR101 is an ultra-pure ethyl ester of eicosapentaenoic acid (Ethyl-EPA).
Hypertriglyceridemia refers to a condition in which patients have high blood levels of triglycerides and is associated with increased levels of heart disease. It is one component of a range of lipid disorders collectively referred to as dyslipidemia. The overall dyslipidemia population in the U.S. is believed to be in excess of 100 million, with over 10 million of those diagnosed with hypertriglyceridemia.

and, a little over 10 years later, i was finally proven correct! ;)


while the journey took a few unpleasant turns, i learned a lot along the way.

thank you to all those who indulged my abridged'ness and taught me over these past 10 years, especially and assuredly, @JL.

"when the student is ready the teacher will appear"

[Planetrader]

Kiwi, I came across this stock many moons ago from a stock site called Bio-Run up. I remember at the time I invested in 3 stocks. AMRN, SQMN and EXAS. I began researching several hours a day on all 3 stocks. I remember the morning that we got great phase 3 results and the stock went to 19. I had about 50k shares but did not sell because of I had not held the stock for a year and did not want to take a 40% tax hit. After ADCON we all know what happen and rode the stock ALL the way down never selling a share. I sold my SQNM around 4.50 and my EXAS around 25 and plow all my liquid assets in to AMRN to end up with my 394k shares. Its true I had only one stock in my etrade account after that.I was not worth 40 million as you stated after my last post that you replied to. I am still not following correct investment rules on this stock because I have still not sold a share. With this stock and the knowledge I have gain on this board and researching lead me to understand this was a blockbuster. I also started taking V 4 years ago and got my wife on it. Both were off label prescriptions. I knew I always have my equity in my business that has continue to grow. So I am sure that and my daily two hrs of research always helped me sleep good at night.This will be my only and last all in....

Plane

[louieblouie]

In 2011/2012 I was testing the waters of the investment world not having a clue what I was doing. Somewhere along the way I saw an article in Seeking Alpha written by Stephen Rosenman and what he was laying out in his article about Vascepa made sense to me. So I bought a few shares, and then some more, and then more..... Then the ADCOM fiasco came and the price tanked. After my brief meltdown and realizing I was small potatoes compared to so many of you - I hitched my wagon to about 30 of you and joined EPADI.

Being a 'girl with a gun' for 30+ years I couldn't offer much to the group due to my lack of understanding of medicine, science and statistics.... I could at least slap a mean glossary together for a bunch of terms I never heard of before EPADI was formed.

Throughout the years - the members of EPADI kept me focused which is really good because I now realize I suck at the stock market and my investment choices. I also suck at math, science, statistics, and a few other things. However, I think I have made some good friends who I have never had the opportunity to meet (Cory the exception) ...and I've had a bit of fun getting to needle the ever brilliant Jason from time to time which in my own perverse way keeps me grounded.

Looking forward to meeting some of you in Vegas.

[kjones3701]

Kiwi

I believe I heard about AMRN from someone on the Genvec yahoo message board. I bought several thousand shares in the mid single digits. Sold half in the $16 range and sold the rest after Adcom. Kept it on my radar and started accumulating again in early 2016.

[circuitcity]

Are we sharing now? OK

Started stock trading in 2008. You know what happened that year and I got in afterwards. SO anything I touched with my finger just had one direction to go, North LOL. That gave me the illusion I am a genius on stock market and never had patience for long term investment. That time, I was mainly after momentum plays and that was when I bought and sould Amazon for like 30% profit. Couple years later I pretty much gave back all the profit and were stuck with several stocks. Then I came cross AMRN at ~$7 in 2013 at a stock forum, meant for a short term, quick money play, but got stuck. AMRN was one of last couple trades before I made the decision to quit stocks and focus on other things in my life, such as work and life.

I kept my words didn't even check two accounts for years (they were full of stuck stocks...) because I was so disappointed with my loss and luck in the market. Until couple weeks ago, out of no where, I logged in my trading accounts and wanted to clean up. I am glad I didn't give up AMRN. And here we are today. I didn't go through the looong waiting time for R-I like you, as I said I completely left everything behind me. But I think I can understand your frustration during all those years and it just seemed never going to end. So have fun at LV or SF parties, you all deserve it.

I used to be on Ihub, but on other boards. New to Ihub AMRN board and did a lot of digging before 9/24 because I have lost track of the stock for so long. I am glad didn't drop it and planning to keep it long term per JL's advice. A lot of good and interesting folks here and that is why I am talking. Glad to be here.

[ORBAPU]

I can't remember what caused me to look at Amarin, unlike the dates 10/16/2013 and 9/24/2018 that I remember quite well. Back in the day, I think the Apple iPhone stock app carried articles by Seeking Alpha and/or Motley Fool and that's likely where I noticed it. Took first position end of May 2013. Had just retired April 1 so I had some cash and time to amuse myself searching for investment ideas. Oh, and I opened our trading account with great anticipation in December 2007. So began my education in the school of investment hard knocks. Didn't sell though, stubborn that way.

By the ADCOM, I had 5,000 shares @~$7 so when it dropped to ~$2, I didn't panic and I generally don't sell unless it looks hopeless.

Not sure when I joined iHub but not right away. People kept mentioning iHub on yahoo and Stocktwits so I joined too. Anyway, the more I learned, the more I added, even at $0.80.

Being the curious type and my Dad dying of his 3rd heart attack at 67, I read everything that folks posted. Probably have a few hundred articles bookmarked. JL's asymmetrical bet notion and scientific perspective as well as HG, Zum, Sam, and others were influential . My wife and I started talking EPA 500 2-1/2 years ago and have experienced positive effects.