Your insight here is appreciated and your work astounding. Thank you for your time
I believe your points all are validation of Dr. Liau’s overall implication that the longer this trial goes, the better the results will be. I believe process improvements, optimization, and insights continued to benefit patients as the trial proceeded. The question is whether the FDA viewed these as negative and confusing and implemented the hold to avoid additional optimization or changes. We’ll get more insight with final results.
Finally...good luck to investors, but more importantly, good luck to GBM patients. This vaccine still holds the promise of being a monster breakthrough technology in the fight against one of the worst cancers known to man. The scientific community is anxiously awaiting the study results. If this works on GBM, the next advance should be for it to work on all solid tumors.