NorthWest Biotherapeutics Inc (NWBO): There's also a big confounding facto...

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Re: flipper44 post# 189286

Thursday, 09/13/2018 11:13:29 AM

Thursday, September 13, 2018 11:13:29 AM

There's also a big confounding factor here

the patients with undiagnosed MGMT status are likely to be the ones with less surgical resection as you usually need quite a lot of DNA for bisulphite treatment before MSP or sequencing. Hence these patients probably failed genotyping because of the lack of tumour material. And we know that greater surgical resection is associated with better prognosis

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