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flipper44

08/17/18 8:08 PM

#186467 RE: Lykiri #186464

So three crossover patients received DCVax-l after recurrent surgery, at least one of them being from the treatment arm. Good point.

exwannabe

08/18/18 5:46 AM

#186473 RE: Lykiri #186464

Good catch from the Sunday story.

Another takeaway though is that again we see how the trial has been effectively unblinded. Upon crossing, they learn if they had been shipping DCVax-L. So well over half the trial is effectively (if not technically) unblinded. And perhaps the final 30+ is also unblinded.

With that much of the trial data unblinded, they have a damn good idea what the ITT curves look like. And the trial marches on well past the designed analysis.