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fearfrost

10/19/06 6:55 PM

#1568 RE: neuroinv #1567

Good information, thank you Neuro. I always appreciate your insightful posts
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gfp927z

10/19/06 8:12 PM

#1569 RE: neuroinv #1567

Thanks Neuro. Well, if they've pushed the timetable estimate for the BP deal back even more, to 1H-07, then I don't see how a PIPE is realistically going to be avoided (barring some unexpected event in the next several months that sends the stock price skyward and triggers a large amount of warrant excercising - something like blowout great Schizo results, or a final Euro patent victory).

Your discussion with Dr. Karran sounded interesting. I'm not sure I followed your last comment though, ie - did Karran not seem to disagree with Lilly's position that they don't need Cortex's IP, or did he not seem to disagree with your comments that a partnership would be good for Lilly? Thanks for all your insights Neuro.

(BTW, it looks like I just used up the last of my 15 free daily I-Hub posts, so will see you guys later).
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Aiming4

10/19/06 9:04 PM

#1572 RE: neuroinv #1567

Thanks Neuro. I have a feeling Lilly's stance:

...and then added that Lilly isn't convinced that they need Cortex's IP--i.e. they still hope to win on appeal of the patents.

explains a lot of the macro trends in COR that we are seeing from our vantage point outside of the black box.

This stance concerns me because it suggests that Lilly believes they can break the broad usage patent, *and* compete with Cortex in the lab.

They must feel strongly about both of those things, because assuming Lilly is bullish on Ampakines it's a huge gamble to let Cortex sign with another BP partner.

Especially when Lilly could be that partner for the relatively paltry sum of $30M or so... Aiming4.
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meixatech

10/19/06 10:52 PM

#1577 RE: neuroinv #1567

A few years back Computer Motion and Intuitive Surgical were locked in a series of patent battles. Multiple suits in multiple courts. Hugely expensive for both sides. Looked like Computer Motion, the smaller company, was gaining the upper hand... suddenly MERGER! I don't think anyone expected it to happen, but it made lots of sense and lots of investors ultimately quite happy.

OK. Lilly and Cortex? Come on, Neuro, if Lilly and Cortex were in the final stages of partnership talks, do you really think a Lilly executive would give the biggest neuro-biotech “gossip” any hint that this was happening? I don't think so.

I believe that Lilly is the BP that COR will partner. As you said, Neuro, it makes sense. Indeed, it appeared that Stoll gave a hint at the Bear Stearns Conference that this was so by using Lilly data in his presentation: Gfp's #1179 - “Lilly's LY-503430 (slide 10)- I think this was the first time Dr. Stoll had a presentation slide showing Lilly's phenomenal preclinical Parkinson's results with their AMPA upmodulator. 23 days of dosing showed a dramatic improvement in this preclinical model, demonstrating the huge potential of the high impact approach.” For a such a limited time to present, I still think it is extraordinary that not only does Stoll actually have a Lilly slide, but that he would devote time talking about a Lilly compound.