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Replies to post #141962 on Anavex Life Sciences Corp (AVXL)
nidan7500
02/21/18 1:57 PM
#141965 RE: Mikesc #141962
It has become increasingly clear that misregulation or mutations of epigenetic enzymes are at the basis of a broad range of syndromes and diseases [41]. Mutations in epigenetic enzymes are frequently observed in cancer [42], intellectual disability [43], neurological disorders such as Alzheimer’s, Parkinson’s, and Huntington’s disease [44], and autoimmune diseases such as rheumatoid arthritis [45–47] and type 1 diabetes [48]. Most studies have been performed in cancer: ~30% of all driver genes characterized in cancer are related to chromatin structure and function [42]