Replies to post #141730 on Anavex Life Sciences Corp (AVXL)

[XenaLives]

I don't know if there is a biomarker for "sleepiness" but sleep disorders can clearly be identified.

As I've tried to point out - the quality of sleep and REM is an important factor. You are right - insomnia is a possible characteristic of pre Alzheimer's, but more broadly it is a characteristic of CNS illness and also illness that is diagonsed as psychiatric which may be rooted in organic dysyfunction.

It really is an important biomarker that needs a lot more study.

[LakeshoreLeo1953]

And there in lies the rub about the original post.

Addressing insomnia, etc is indeed a measurable endpoint
which could lead to "relief" from the compound.

I doubt seriously however that it is used as diagnosis or a determinant for for candidate enrollment or identification within an AZ trial.

All the equivocation in the world will not alter that reality.

Now I really would like to get some sleep......I suggest a My Pillow to some who could use the help.