JL if the EPA/AA ratio in RIT are dose to match those in Jelis, then are we supposed to see a 2.8% MACE rate over 4.6 years, ie 0.6% per annum for the RIT treated arm? That would be quite an improvement considering that RIT composite rate is 4.8% so far. How worse than 0.6% can it be? 2%? 3%? That would still be a RRR well above 50%... Quite onesttly I am scratching my head as to why this trial has not been stopped yet.