Replies to post #112804 on Amarin Corp Plc (AMRN)

[Whalatane]

Ralphey Re Zetia and sub sets

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there are high-risk subgroups among this population that could gain, argued Robert Giugliano, MD, a cardiologist at Brigham and Women's Hospital, Boston, Massachusetts, who presented the findings in a clinical-trial update at the European Society of Cardiology 2015 Congress.

"In this particular [prespecified] analysis, we focused on the 4933 patients (27%) enrolled [in IMPROVE-IT] with diabetes. We know from prior work among diabetics that ezetimibe not only reduces LDL cholesterol but also reduces triglycerides and other atherogenic lipoproteins and also reduces insulin resistance," he told the meeting.
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Now, "we see a very consistent pattern of a greater benefit with ezetimibe for diabetic patients vs nondiabetics [in IMPROVE-IT], with a 24% reduction in myocardial infarction and a 39% reduction in ischemic stroke, and no safety signals," Dr Giugliano reported.[/color]
"We believe these findings are supportive of intensive lipid therapy in diabetics," he added.

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Suggest you consider Zetia for your diabetic CAD patients ( maybe even pre diabetics ...I'm prescribed it now ) ...its generic .
Also serves as a marker for Vascepa to beat !!!

Kiwi

[rafunrafun]

Funny...

Today: "we cant know until the study is completed"

Two days ago: "my experience has revealed that this med is not the game changer I had originally believed it would be"

[rafunrafun]

"In general I see about a 25% reduction - however, that level of reduction can easily be obtained with dietary change"

.... and? Dietary change obviously helps to reduce the chance of having a CVD. So how is it not beneficial to lower TG by 25% ON TOP OF DIET CHANGE?