Replies to post #115854 on Anavex Life Sciences Corp (AVXL)

[McMagyar]

I disagree..

If at 52 weeks the average responders n=19 changed their dosages to higher A2-73 and less DZP or a combination
Of those actions including dropping DZP altogether..

And those n=19 now join the slope and Scoring of the Super Responders
( those scoring ahead of where the study started) and we are now over 2 years into study for some I believe..

Then you conclusive evidence..and here is why..

Animal studies.. I have read the sigma1 response /system is very similar in rodentia population to human..( why so many Parkinson's, Epilepsy foundations and researchers use them). How many Animla studies have conclusively shown the A2-73 effect? It is not hundreds but over 10? With ZERO failures!

Finally you have ALL the previous data from 10,000 's of Alzheimer patients and you can simply prove
Efficacy by defacto ODDS..


The ODDS that in this population that
1 in 25 patients is doing better one year. ( or more) from Alzheimer diagnosis..is slim.. ( people don't accidentally commit themselves or their loved ones to Alzheimer's clinics or studies these people are sick).

Now take that times 6 out of 25..
Those numbers are CRAZY All by themselves.. they are beyond lottery.


BUT if a Super Majority of the n=25
Are doing better than when the Trial started 2 years ago or are headed that way.. than when an oddsman presents the probability that the effect is "accidental" the number would be so ridiculous as to be IMPOSSIBLE.


So yeah. We can have conclusive evidence with n=25.

Anavex NOW has been waiting to see
These numbers to confirm what Anavex Now already believes.


Anavex NOW