BTW, the question is, does A2-73 restore CNS Homeostasis or not? And then what happens? If, Y then game over. Since no known patient has ever stabilized, much less recovered, form AD how is the question of statistical confidence even relevant. We miss the point if we try to debate/agree on n. That thinking is what got us the last 50 years.....zippo, nada, ziltch...It's a breakthrough. Have a great day.