The "black box" is of course Homeostasis. The evidence is building around CNS diseases and the efficacy models being shown in mouse trials. It is not a leap to say this is more than just chance/luck of the draw. Independent self funding trials seem certain at this point as a broadly implemented next step. The whole FDA new structure thing could not be better planned, even it is only millions of little family prayers being answered. This whole thing may just flash over at any moment, that is what BT's do.
Dr. M has bigger issues and I would like to think he has anticipated the enormous negative power of combined big P, various tutes, some media when they realize (probably already have) the scope of the threat that A2-73 (etal) presents. There are those who will say that just b/c A2-73 works it's not (fill in the blank).
Could it be that Dr. M sees this Big P threat and is surrounding his opponents(as a good Ninja would, silently) with many small self funded trails on rare diseases. The time for the AD solution will come at it's best speed, we can sense that. We have seen many times in Bio that just b/c something is right does not mean it is successful. If we can see this coming then we can be certain that Big P does also and that they will/are bring(ing) on massive/negative resources to crush AVXL. This is my own read of the current situation. I am not being negative just aware of what to expect in the systems dynamics about to play out if A2-73 continues to prove the thesis which will destroy big P. If this does happen for Anavex then I predict they and the FDA fast track program will sweep the field.
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