17...Saw that and thought the same thing. ( I am not qualified in medical science to say this..but) I do have some limited experience with BT (in semiconductor physics). When BT happens new plausible explanations jump to the surface. The BT then becomes the bridge to other solutions previously not considered. Maybe we are will see some of that with A2-73.
Excellent post Amateur. I think the Muscarinic AND a2-74 metabolite also being a Sigma 1 agonist are the major keys to successfully empowering the Chaperone. The Muscarinic is making the path easy to navigate and the metabolite is allowing the Sigma 1 more time to perform..
I know that is simple.. but that is how I see this.. simple.
What struck me is that A2-73 reduces insomnia. I have heard that when we dream our brains are cleansing themselves. Perhaps that is what A2-73 does and the reduction in insomnia is a sign of that. Anyway, just a thought.