My only hesitation about monotherapy steps from our July 2016 AAIC poster:
"Positive MMSR score effect with ANAVEX 2-73 alone and no notable difference observed on MMSE score between ANAVEX 2-73 alone and ANAVEX 2-73 with donepezil."
Perhaps we'll see improvements in other areas (besides MMSE) if all trial participants did in fact switch to monotherapy?