Replies to post #68175 on NorthWest Biotherapeutics Inc (NWBO)

[Evaluate]

You wrote:

An average GBM tumor contains 1011 cells, which is on average reduced to 109 cells after surgery (a reduction of 99%).

Umhh, excuse me?
109 remaining cells out of 1011 cells is not a 99% reduction.

In other words, if there was a 99% reduction, there would only be 1% remaining, and 1% of 1011 cells would be merely 10 cells remaining.

[Reefrad]

You're using a radiographic (xray) experiment to prove the lower limit of size for MRI sensitivity?

Apples and oranges. No relation whatsoever.

[Do Due Dilligence]

How some say there are no psPD in the CUA do not understand that they need comparison MRIs to make that determination of whether it's "true disease"; and so of course if they confound it with vaccine, it would become "Indeterminate". But I digress.

There is the fact that they used both RANO and Mac Donald criterias. There are sometimes conflicts between both sets to determine progression or pseudoprogression so I guess thoses cases happening at 2nd scan got put into the indeterminate section.

But as I told you in previous posts, there is no way to be sure that there are psPD in that section. In Linhares study they found only 2 PsPD among 70 patients using RANO criteria. We have already 33 cases confirmed in DCVax-L study, though I don't know how many patients in total underwent screeening.

[sentiment_stocks]

RK... thanks for this very thorough post. It was very helpful and I appreciate all the DD you put into this.
I read through the entire thing. Of course, part of it was late last night and the phone fell on my face as I fell asleep, lol! ... so I got back to it this morning. :)

[AVII77]

Thanks RK for your detailed response. I'm still up at the lake and only have my phone so will offer some comments later this week.