Replies to post #58093 on Anavex Life Sciences Corp (AVXL)

[TomP1]

no notable difference between ANAVEX 2-73 alone and ANAVEX 2-73 with donepezil (ANAVEX PLUS) were observed.

So whether patients take A2-73 as a standalone or in combo with Donepzil, it seems to make no difference. This is in controdiction to the animal models who did predict a positive effect when combined.

I will take it a step further: so many AZ drugs looked great in animal models and yet they have all failed once tried on humans. So far we seem to be the only ones who have a molecule that actually helps in humans.

BUT, to be validated in bigger and more trials, starting with 26, 52 week data and a p3