You missed the point I tried to make. In the Ph 2A trial, patients had been on donepezil probably longer than 12 weeks before the trial even began. We know after 12 weeks, DONEPEZIL DOES NOT WORK. Take a patient that has never been given donepezil in their life, give it to him along with 2-73, then evaluate for synergy between the two. That is fair assessment and replicates how the mouse studies were run.