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loanranger

08/28/14 7:10 AM

#97634 RE: BonelessCat #97629

From the Abstract:
"The compounds were tested for efficacy and cytotoxicity in Vero E6 cells. Several compounds showed promising results and little cytotoxicity, and may be further evaluated in animal models."

From the Conclusions:
"The compounds were tolerated well by the mice and showed slight efficacy against the mouse-adapted Ebola virus.
More experiments need to be performed to determine if different concentrations are efficacious in mice.
The preliminary data are promising and more in vitro and in vivo experiments are being performed with these compounds."

You said:
"...there is independent proof of concept from a highly reliable government funded lab..."


The definition of "Proof of concept" varies by and even within field of endeavor. This one is from the publication "Clinical Pharmacology & Therapeutics":
"Proof of concept (POC) may be defined as the earliest point in the drug development process at which the weight of evidence suggests that it is “reasonably likely” that the key attributes for success are present and the key causes of failure are absent."

Do the quoted statements, or any other statements in the presentation, show that "proof of concept" was established?



edit: http://www.nature.com/clpt/journal/v87/n3/full/clpt2009286a.html

Rawnoc

08/28/14 9:12 AM

#97643 RE: BonelessCat #97629

I have no proof either way if the science works and neither does anybody else.

I'm sorry if the company's 9 years of failed claims is offensive to anybody, but since believing the science works involves little more than putting trust into shady, sleazy characters, their historical and ongoing credibility is vital. And it stinks on ice.

I can't see the words in your image but somebody else says the conclusion is "slight efficacy" ???? That's proof of science working? ROFL!!! I'll just go Diwan's statement specifically claiming that Ebolacide was originally a failure and a "slight efficacy" in rodents is a yawner. It's new and approved now? Spare me. We all know NNVC won't get a dime for it.