Bioelectronics Corp (BIEL)

[GetSeriousOK]

I took that quote directly from your post but you say I'm "wrong?"

Be specific, wordsmith. Are you claiming that "Control of Postoperative Pain with a Wearable Continuously Operating Pulsed Radiofrequency Energy Device: A Preliminary Study" satisfies the CMS requirement for reimbursement under the NOPAIN Act?

It's a simple Yes or No. You allude to "no" when you say "I would think that the noted study would not suffice; not robust," but then what is the point of your post here?

And what do you mean by "the cumulative effect of more robust clinical trials keeps surfacing?" Be specific. Name one such "robust trial."

Regarding Rawe's clinical trial: SO many things wrong with this study. Let's review:

1. Only 18 patients total.
2. Conflict of interest: it was not an independent study.
3. The CONCLUSION says nothing about opioid use. (I assume you understand the importance of the conclusion.)
4. Opioid use was not an endpoint of the trial. This trial didn't even HAVE endpoints.
5. opioid decrease in active group was NOT SIGNIFICANT (p=0.07

You don't seem to understand the significance of #5. There's no way to sugar-coat this, although the researchers tried by eliminating one outlier patient, a practice called "cherry picking," making the opioid results inadmissible as clinical evidence.

The means were 11 pills per patient in the active group and 18.1 pills per patient in the placebo group, representing a 68% increase in narcotic medication use in the placebo group (P = 0.07, nonsignificant increase). However, with the outlier (patient 10) excluded, the mean narcotic pill use becomes 18.1 for the placebo group and 8.5 for the active group (P = 0.002, a significant difference).

Anyone who has ever done research or works in the field of research (and that includes the CMS) knows that you can't just exclude outliers in your data until you get the results you wanted. When the CMS says they require "evidence," well, wordsmith, they require "evidence," not "yeah but if you exclude this one patient...."

I'm sorry, you wanted me to ask Ian Rawe why he tried to pull off this cherry-picking bullshit in a journal? And then share his response with you? That's what you're criticizing me for not doing?

And finally, what is your point about Humana? It was one of your main cheerleaders, Hawk, who introduced that to the forum, and he asked for thoughts, but you mock those who replied with thoughts?

And when you say "it's never been covered by any insurance....." You know that the CMS is Medicare, and Medicare is insurance, and the NOPAIN Act is all about insurance reimbursement? Yet you're still LYAO?