Wednesday, March 13, 2024 9:48:47 PM
I think that some of the 99, not all, crossed over, and they are classified as follows:
- The 64 patients included in the rGBM arm. All of them were real progressors.
- Part of the 18 PFS censors (99 total - 81 PFS events). Some of them were pseudo progressors from SOC and other were progressors whose real moment of progression could not be clearly established or that didn't meet the criteria to be included in the rGBM arm (screening for the rGBM arm if I may say). None of these 18 or less patients were included in the rGBM arm because of the reasons I explained in my previous posts.
Regarding the other 17 (81 - 64), I think most of them were patients that didn't cross over because they very sick or died without crossing over.
I don't understand what plan you are referring to. Also I guess the screening details for inclusion in the rGBM arm that was compared to external control arms was not included in the protocols you mention, because those protocols were from before if I understand well.
I'm not suggesting that. I'm not saying that they necessarily lived longer, and if they did, I think it was because of DCVax. Also I don't understand why do you think this would give any arguments to the shorts. I actually think this is positive and I am very bullish about the trial results as I have been always.
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