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Monday, March 11, 2024 9:03:24 PM
they started receiving DCVax from pseudoprogression, so their OS could not be used for the purpose of comparing against SOC after that.
GC, this statement of your's implies that the control patients (some number or all of them) all crossed over due to psPD and began receiving DCVax.
That would mean (as I understand your theory) that after screening for psPD caused by chemo/rad and not finding it, some theoretical number of your's of control patients then developed psPD after entering the trial due to chemo/rad (it couldn't be due to DCVax because they hadn't received it). Then these theoretical control patients began receiving DCVax-L, and were censored.
Let me begin by stating that none of the protocols that have been leaked (and I have about 4 of them) ever alluded to such a plan, so this censoring would have been agreed to near the end of the trial.
Next, if the control patients that lived longer were also psPD due to chemo/radiation, exwannabe and the entire short crew would swoop in here and tell you that is why the control arm did so well, and "lived longer". This was an argument that I had with ex and Avii a hundred times. So... if that is what you are suggesting, I reject that argument wholeheartedly, as I did with them, a hundred times.
Perhaps I am misunderstanding your theory... but I am reading your words, and that is what I understand them to be stating.
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