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Friday, 10/07/2022 9:02:49 PM

Friday, October 07, 2022 9:02:49 PM

Post# of 462160
To: Dr. Christopher U. Missling MS PhD MBA and all the employees at Anavexx Life Sciences, AVXL shareholders eagerly await the following list of catalysts:

> Top-line data ANAVEX®2-73-AD-004: Potentially pivotal Phase 2b/3 AD clinical trial – expected fall 2022
> Data of 48-week OLE PDD Phase 2 study – expected by end 2022
> EXCELLENCE completion: Potentially pivotal Phase 2/3 pediatric RTT clinical trial – expected by end 2022
> Initiation of ANAVEX®2-73 imaging-focused Parkinson’s disease clinical trial – expected 2022
> Initiation of potentially pivotal ANAVEX®2-73 Phase 2/3 Fragile X clinical trial – expected 2022
> Initiation of potentially pivotal ANAVEX®2-73 Phase 2/3 clinical trial for the treatment of a new, rare disease indication – expected 2022
> Initiation of ANAVEX®3-71 Phase 2 clinical trial for FTD, schizophrenias and Alzheimer’s disease – expected 2022

Good luck and GOD bless,
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