Amarin Corp Plc (AMRN)

[Pharmacydude]

LTTRO
Both groups, control group and EPA group, we’re receiving estrogen. Blood levels of Apo B were taken at four different times. When you look at the table you see the control group Apo B level went from 123.4 to 121.5 and to the right you see NS - not a stat sig change from first (baseline) to last measurement WITHIN the group. For the EPA group you see an initial level of 124.8 and a final level of 116.2 which represented a stat sig reduction in the level from baseline WITHIN THE GROUP. Both groups had a reduction in the level from baseline to endpoint which could be the result of the effects of the estrogen on Apo B. The key here is that you have to compare the levels BETWEEN THE GROUPS to see the effects of EPA. The cropped table does not show that the P with the cross is indicating the “intergroup difference” which is the value showing the effect caused by the EPA and ALL 4 measurements showed the differences to be NS (not stat sig difference between the 2 groups). Judge Du stated there was a state sig difference BETWEEN THE GROUPS and therefore the change in Apo B was obvious. It wasn’t.