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Re: sentiment_stocks post# 248749

Wednesday, 10/23/2019 5:23:34 PM

Wednesday, October 23, 2019 5:23:34 PM

Post# of 689382
Thanks Senti for the reply. I remembered that Optune used two year data to estimate 3, 4 and 5 year survival. But I need to find that article to be sure. But you had confirmed it with the post below. When asked where is the 13% of 5 year OS coming from, Optune would need to be ready to support that claim.

The problem with the Optune data, as Flip has pointed out so many times, is that Novocure stopped the trial after everyone had been in it for just 2 years, basically freezing the estimated KM survival data at what it showed then, which was 29.3% for those 43 patients who'd worn the device for 90+ percent of the time. That's why the 3, 4 and 5 year survival percentage for those 43 patients is 29.3% every year. It was frozen in time. This KM data implies that at the 5th year, there were 13 from the 45 alive. The fact that Optune doesn't confirm this data, at the real-time 3, 4 and 5 year mark, argues that this isn't what ended up to be the case.

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