Mellowmood77 Tuesday, 09/17/19 12:29:06 PM Re: Whalatane post# 214783 Post # of 220248 Clinical ASCVD would indeed be under secondary prevention and an event is not required: Documented coronary artery disease (CAD; one or more of the following primary criteria must be satisfied): • Documented multi vessel CAD (≥50% stenosis in at least two major epicardial coronary arteries – with or without antecedent revascularization); • Documented prior MI; • Hospitalization for high-risk non-ST-segment elevation acute coronary syndrome (NSTE-ACS) (with objective evidence of ischemia: ST-segment deviation or biomarker positivity). 2. Documented cerebrovascular or carotid disease (one of the following primary criteria must be satisfied): • Documented prior ischemic stroke; • Symptomatic carotid artery disease with ≥50% carotid arterial stenosis; • Asymptomatic carotid artery disease with ≥70% carotid arterial stenosis per angiography or duplex ultrasound; • History of carotid revascularization (catheter-based or surgical). 3. Documented peripheral arterial disease (PAD; one or more of the following primary criteria must be satisfied): • Ankle-brachial index (ABI) <0.9 with symptoms of intermittent claudication; • History of aorto-iliac or peripheral arterial intervention (catheter-based or surgical). Primary prevention requires you to have diabetes type 1 or type 2 plus one additional risk factor in the reduce-it trial. If you have diabetes and your additional risk factor is, say, ankle-brachial index (ABI) <0.9 with symptoms of intermittent claudication, or anything from the previous table, you will be counted as secondary not primary.