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Friday, 06/21/2019 9:34:59 AM

Friday, June 21, 2019 9:34:59 AM

Post# of 459493
Good morning board---I was wondering if Cystic fibrosis could be a possible candidate for Anavex treatment?
It seems to be in our wheelhouse, a genetic mutation, with over 1500 mutations...


The CFTR protein is a channel protein that controls the flow of H2O and Cl- ions in and out of cells inside the lungs. When the CFTR protein is working correctly, ions freely flow in and out of the cells. However, when the CFTR protein is malfunctioning, these ions cannot flow out of the cell due to a blocked channel. This causes cystic fibrosis, characterized by the buildup of thick mucus in the lungs.

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