NorthWest Biotherapeutics Inc (NWBO)

[sukus]

AVII,

I believe the vaccines are not futile.

Below are to refute your futility theory.

The surrogate PFS endpoint was based on the patients tumor progression. I believe that is the case.

Before:
The tumor was getting bigger ==> the tumor progressed ==> DCVax futile.

Now:
With better understanding of immunotherapy mechanisms of work which was supported by BMY:

The tumor was getting bigger ==> but oh the tumors were filled with T-cells ==> induced tumor necrosis ==> the tumors shrunk afterward ==> better quality of life ==> patients life extended ==> patients survived.

You see, they originally saw tumor progression were actually a signal that T-cells were infiltrating the tumors and secreting toxins to cause tumors to die and not spread.

Imo..