Sunday, March 10, 2019 2:40:08 PM
NEWS!!! March 4, 2019 Third party paper on cellular recycling.
https://www.anavex.com/anavex-life-sciences-reports-publication-of-new-data-that-show-anavex2-73-induces-cellular-recycling-process-linked-to-the-prevention-and-treatment-of-age-associated-diseases/
access to paper
https://www.mdpi.com/2073-4409/8/3/211/htm
What is proteostasis?
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=147258047
What is autophagy? (from nidan7500) video from Investor 2014.
https://www.news-medical.net/health/What-is-Autophagy.aspx
This MOA applies to the aging process in general:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=147257995
Good summary of the autophagy paper:
https://parkinsonsnewstoday.com/2019/03/07/study-reveals-neuroprotective-mechanisms-anavex-2-73/
Response to above from Falconer:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=147361303
Now we have the Firetruck and Garbagetruck (from Investor2014):
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=147358699
Interplay of endoplasmic reticulum stress and autophagy in neurodegenerative disorders.
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=147423046
A series of posts on autophgy from georgejjl
#184496 Autophagy and mitophagy in ALS.
#184495 New preclinical data establishes ANAVEX®2-73 as a modulator
#184494 Role of autophagy in the pathogenesis of multiple sclerosis
#184493 Dysregulation of autophagy and mitochondrial function in Parkinson’s disease
#184492 Impairment of the macroautophagy: a possible hallmark of
#184491 Elimination of ß-amyloid plaques via macroautophagy
#184490 Protein Misfolding and Accumulation as Root Cause in Neurodegeneration
First post in series: https://investorshub.advfn.com/boards/read_msg.aspx?message_id=147417660
There are no posts mentioning autophagy on this board prior to 2015.
2015 posts mentioning autophagy - one each from georgejjl and TrueTrades:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=118317394&txt2find=autophagy
Link to the entire paper referenced by TrueTrades:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807076/pdf/mol.113.087809.pdf
2016 posts mentioning autophagy - three from georgejjl:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=121979414&txt2find=autophagy
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=122985309&txt2find=autophagy
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=126356651&txt2find=autophagy
Potential Roles of Mitochondria-Associated ER Membranes (MAMs) in Traumatic Brain Injury (from george jjl in 2017)
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=129858549
Autophagy not mentioned again until two posts on 3/9/18 by mapman1010. It's interesting that it was almost precisely one year before the current paper:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=139184780&txt2find=autophagy
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=139185523&txt2find=autophagy
Discussion of the above:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=140322574&txt2find=autophagy
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=140431749&txt2find=autophagy
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=140576574&txt2find=autophagy
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=140709556&txt2find=autophagy
Autophagy other 2018 mentions:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=141039429&txt2find=autophagy
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=141231591&txt2find=autophagy
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=141689338&txt2find=autophagy
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=141909594&txt2find=autophagy
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=141925525&txt2find=autophagy
ER–mitochondria signaling in Parkinson’s disease (from mapman's link to article post below)
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=142355746&txt2find=autophagy
PDF of the article cited:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832754/pdf/41419_2017_Article_79.pdf)
Autophagy and late Alzheimer's:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=143131392&txt2find=autophagy
Amateur17 linked to this article on research done in Australia in 2018:
Alzheimer's tied to brain's 'waste removal system'
https://www.medicalnewstoday.com/articles/322857.php
Sokol post touches on the subject and gives a comprehensive overview of research:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=143320176&txt2find=autophagy
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=143320176&txt2find=autophagy
Autophagy was discussed in September 2018 at the New York Academy of Sciences one-day symposium
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=143337580&txt2find=autophagy
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=145735099&txt2find=autophagy
The above links to non public research by Ashutosh Kumar, I found these links:
https://www.eurekalert.org/pub_releases/2018-12/bsp-aam122618.php
More on Dr. Kumar and his line of research:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=147423162
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