NorthWest Biotherapeutics Inc (NWBO)

[CogDiss 1188X]

Ex, your reply contains several points worth considering in depth — thanks for sharing them. A dialogue here would be an opportunity to understand some key issues around cancer treatment, both from a patient perspective and more indirectly as to how those issues might impact one’s investment thesis around a company such as NWBO. Sarcoma and DCVax-Direct being only one such touchpoint.

The recent advances in immuno-oncology are a key area of focus for me now, which is how I hit on Coley’s toxins once again. Presumably like you, when I saw references to Coley (in my past investigations of cancer treatments), I assumed his work went nowhere for good reason and skipped it — one only has so many hours in the day after all. I now believe there is more there than met my paradigm-blinded eye.

However, unpacking your comments on targeted therapies will probably be the most fruitful area of discussion, though the history of chemotherapy and immune therapy are certainly relevant — both as (potential) patients and as those interested in NWBO.

A lot of big topics - a couple of which I need to dig into further, as well as to figure out how to break down so things don’t spin off into the ether.

More to come