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Friday, 12/07/2018 3:47:47 PM

Friday, December 07, 2018 3:47:47 PM

Post# of 425931
Received from IR
Hi Scott- Great question. I had to dig into the data a bit.

Yes there was a 38% RRR in a population with lipid values similar to the STRENGTH study. As per that data regarding consistent results, data is reported for results in the subpopulation with TG>200 mg/dL and HDL-C <35 mg/dL and the result was a hazard ration of 0.62 (or RRR of 38%). This was not the primary endpoint of the study. We did not enroll patients intentionally based on this criteria. But it was a pre-specified sub-population. See page 17 per the following link:
https://investor.amarincorp.com/static-files/7eed9f2b-3f7a-493f-9113-99d981a198b1.




I hope this helps,
Elisabeth

Elisabeth Schwartz, Sr. Director of Investor Relations and Corporate Communications, Amarin Corporation plc
1430 Route 206, Bedminster, NJ 07921
Direct Number 908.326.2569 | Mobile 201.674.7876
Email: elisabeth.schwartz@amarincorp.com

_________________________________________________
Notice to Investors Regarding Forward-Looking Statements: Recipients of this message who are investors or potential investors in Amarin Corporation plc. (Nasdaq: AMRN) are reminded that any forward-looking statements included in this message is subject to risks, uncertainties and other factors which may cause our actual results to materially differ from any future results expressed or implied by such forward-looking statements. Investors are cautioned to not place undue reliance on such statements and to review the discussions of forward-looking statements and Risk Factors in our annual report as filed with the U.S. Securities and Exchange Commission.



From:
Sent: Thursday, December 6, 2018 12:44 PM
To: investor.relations@amarincorp.com
Cc:
Subject: Citi Call

Hi,
On the call with Citi yesterday JT said the following about the strength trial “But I hope they succeed. They're talking about results in 2020. They're studying a slightly different patient population. They're studying patients with elevated triglycerides and low HDL. Elevated triglycerides, they defined as 200 above. We had a 38% relative risk reduction in that higher risk patient population.”
What 38% reduction was he talking about. Is this reduction from reduce-it? Is this information that has been published or soon to be published? Just need clarity.



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