Friday, December 07, 2018 3:47:47 PM
Hi Scott- Great question. I had to dig into the data a bit.
Yes there was a 38% RRR in a population with lipid values similar to the STRENGTH study. As per that data regarding consistent results, data is reported for results in the subpopulation with TG>200 mg/dL and HDL-C <35 mg/dL and the result was a hazard ration of 0.62 (or RRR of 38%). This was not the primary endpoint of the study. We did not enroll patients intentionally based on this criteria. But it was a pre-specified sub-population. See page 17 per the following link:
https://investor.amarincorp.com/static-files/7eed9f2b-3f7a-493f-9113-99d981a198b1.
I hope this helps,
Elisabeth
Elisabeth Schwartz, Sr. Director of Investor Relations and Corporate Communications, Amarin Corporation plc
1430 Route 206, Bedminster, NJ 07921
Direct Number 908.326.2569 | Mobile 201.674.7876
Email: elisabeth.schwartz@amarincorp.com
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From:
Sent: Thursday, December 6, 2018 12:44 PM
To: investor.relations@amarincorp.com
Cc:
Subject: Citi Call
Hi,
On the call with Citi yesterday JT said the following about the strength trial “But I hope they succeed. They're talking about results in 2020. They're studying a slightly different patient population. They're studying patients with elevated triglycerides and low HDL. Elevated triglycerides, they defined as 200 above. We had a 38% relative risk reduction in that higher risk patient population.”
What 38% reduction was he talking about. Is this reduction from reduce-it? Is this information that has been published or soon to be published? Just need clarity.
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