Monday, November 05, 2018 6:37:53 PM
I looked through you numbers and could not figure out where you got 4266 as the number of secondary events? (I used the original chart in the NEJM) and came up with 4028 (or 4160 if counting their rather confusing cardio revasc numbers by the urgent and elective categories). Regardless of the way, I didn't get a number as high as 4266. These modeling percentages for comparison to REDUCE-IT would be 138.6% or 143.1% respectively. Could you tell me where 4266 came from?
Also, I think 180% is pretty generous, but understand your reasoning given the much longer length of average time in the REDUCE-IT trial. I however would love to see the numbers with just a straight comparison of 1.386% (or 146.7% based upon 4266). I think a conservative approach is better for modeling and expectation. (Otherwise one might be disappointed on Saturday or even set expectations among other investors too high.) Thanks for any reply.
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