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Monday, October 22, 2018 7:10:23 PM
So there has to be at least some of those 38 that lived past 36 months.
Here is the curve - redone - with your suggested corrections. Since you've measured the dimensions of those unmethylated groups and determined that we were missing several step downs, I've redone the curves with your suggestions.
I also had 208 step downs on the larger combined chart, but the 197th step down was missing, making it 207... which is what you are stating. I can't remember if it had been noted that I'd missed that step earlier and if that's why you determined it was 207, or if the figures simply supported that it was 207. Either way, it's now 207 due to that missing 197 step down.
So in summary...
331 total enrolled
MGMT+ = 131 patients
minus 44 censors - (3 LTFU ) / 41 alive before 36 months
= 87
minus 56 died
= 31 lived over 36 months
MGMT - = 162 patients
minus 33 censors - (5 LTFU) / 28 alive before 36 months
=129
minus 121 died
= 8 lived over 36 months
39 (or 38 you are thinking) lived over 36 months
Unknown - 38
minus
1 LTFU - patient #4
1 LTFU - patient #46
= 36 unknown
44 lived past 36 months
- 39 MGMT + and -
= 5 (or 6 you are thinking)
Those 5 or 6 look to be from the 38 unknowns. And again, some of those 38 unknown (dating as far back as 2008) really have to have lived past 36 months in order to reach at least 88.2 months. Because that dates back at least 7.35 years from March 2017. So at least one patient would have to have enrolled prior to January 2010.
So I'm assuming we are off by one patient in order to make that 26.4% work.
Suggestions?
![](http://investorshub.advfn.com/uimage/uploads/2018/10/22/gddzjCombined_charts_no_notes_revised_-lykiri.jpg)
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