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Re: Gator328 post# 141883

Wednesday, 02/21/2018 7:20:58 AM

Wednesday, February 21, 2018 7:20:58 AM

Post# of 458981

If 273 is the wonder drug everyone thinks it is



Not everyone here thinks 2-73 is some "wonder" or "miracle" drug. We have posters here with more tempered expectations. I suspect the truth is somewhere in between the most enthusiastic and most pessimistic. All we need to beat is SOC, which isn't a high-bar to clear. For Retts, there is NOTHING. For Alzheimer's, if we can prove stabilization (not reversal) for 6+ months in 25% of trial participants, 2-73 gets approved and is the new SOC. I believe what Missling/Anavex is doing might even bring us above 50% stabilization of patients because of the pain-staking inclusion/exclusion data by using DNA/Biomarkers to determine who will best respond to 2-73. Now, lets say there is a reversal in a small population of patients...now we are talking a whole different ball-game. But reversal IS NOT necessary to gain FDA approval.


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