[quote You have to know the target. How can you have precision medicine if you are not being "precise" in who exactly you giving the "medicine" too?? ][/quote] This is exactly correct thinking IMO and we are on the right path...totally.
He, WE AVXL are breaking/have broken the trial mold here. When ALL BP had their "come to Jesus" moment a while back and each found a way to cancel/walk away from the AD Plaque path, that was the signal. At the very least they recognized/or were told what the new path was/would be. IMO, they are all out retooling for the new approach and they will all be back. AVXL has a clock running and we better move it or we will get run over.
The discovery process here is pretty obvious. We have been given a one lap head start in 4 lap race. As people like Falconer would point out, we are going to cherry pick the first set of pts. When that works,(and it will b/c we get to define success) then the next subset will start but only after a proper assessment of the first trial, and so it will go until all are either addressed or somehow understood. That is 101 level iterative learning process which we can all see coming. Getting started is key, the clock will not be held for us to finish the race. When BP sees what they must do they will leave the starting line on a bicycle, then move to a motorcycle, etc. Life is just not fare. But, we have the start and now we have to act like we earned it and we expect to finish/win. I am not looking for the Nobel prize, just $500/share and I do not care if they buy us or we get it the hard way. Time is critical here, how we use it is what matters now.
