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Re: Jonjones325 post# 138041

Thursday, 01/18/2018 5:02:12 PM

Thursday, January 18, 2018 5:02:12 PM

Post# of 462094
[quoteMissling could have made a crappy MTA with Biogen that gave them the first right of refusal][/quote]

A. BIIB has a dilemma, they have seen a peek at A2-73 and have studied the results from multiple MS researchers, all of which seem to indicate clinical promise unlike anything they have. Partnering to develop any A2-73 trials would likely lead to killing their golden geese. So, they will not move unless timing/PR/FDA and other conditions force them to. It is all easily understood.

B.We all know, No Micro Biotec's like AVXL can afford to sponsor the massive trials being suggested based on past FDA practices....so 21st century precision medicine CA must be applied w/smaller trials based on TBD guidance. This status quo has resulted in the previous ineffective FDA processes and zero pharma NP innovation...brilliant. So....we wait it out while FDA grinds on w/funding/staffing issues of their own.

C. We have a kind of showdown while BIIB continues to get BIG $$$ for MS, patients endure and AVXL is in this long Queue awaiting some kind of god like intervention, IMO.

Them who has the gold makes the rules.

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