Anavex Life Sciences Corp (AVXL)

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Sigma 1 in liver mitochondria

Listened to a CC on GALT about their drug candidate in P2b, shows some promise, but it made me think of 2-73 and the potential with our antagonist. (They are focused on NASH)

First does the liver have any S1R's? I found an interesting abstract by no other than Tangui Maurice, et al. (Our resident genius)

http://onlinelibrary.wiley.com/doi/10.1038/sj.bjp.0704626/full

Its an older abstract, but interesting how our knowledge now has progressed and the answers have filled in over time.

Maybe another disease outside of CNS that Anavex 2-73 or 3-71 could reverse?