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Re: Investor2014 post# 122612

Saturday, 09/30/2017 5:46:09 AM

Saturday, September 30, 2017 5:46:09 AM

Post# of 463992
Further to this regarding A2-73, my guess is that a "Basket Trial" could be in play.

A basket trial (bottom) involves multiple diseases or histologic features (i.e., in cancer). After participants are screened for the presence of a target, target-positive participants are entered into the trial; as a result, the trial may involve many different diseases or histologic features. A master protocol for a basket trial could contain multiple strata that test various biomarker–drug pairs. Statistical approaches are not depicted in this figure.



Thinking of Ariana, perhaps the time is going into identifying a target and target-positive participants across specific endpoints applicable across say PD and AD, but perhaps not Rett, which I suspect will be executed standalone.
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