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Re: MycroftHolmes post# 93901

Wednesday, 03/01/2017 10:31:27 PM

Wednesday, March 01, 2017 10:31:27 PM

Post# of 462470

in basal conditions, s1R activity triggers a moderate ROS increase, putatively used as a physiological signal



A signal to do what and by whom? Why is a signal even needed during basal conditions? I just don't understand why the sigma receptor would want to generate reactive oxygen species (ROS) at any time? What does that trigger and why (during basal conditions)?



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